α-Ketoglutaric acid

α-Ketoglutaric acid
α-Ketoglutaric acid
α-Ketoglutaric acid
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α-Ketoglutaric acid (CAS No. 328-50-7) is a high-purity compound used in cell culture media to support energy metabolism and amino acid biosynthesis. As an intermediate in the TCA cycle, it helps maintain metabolic balance and promotes cell growth in systems using CHO, HEK293, and other mammalian lines. Supplied in 25 kg fibre drums and stored at 2–8 °C, it’s available with a monthly capacity of 3 tons to meet both research and production needs.

  • CAS No.: 328-50-7
  • Molecular Formula: C₅H₆O₅
  • Purity: 99% min
  • Appearance White to yellowish crystalline powder
  • Molecular Weight 146.10 g/mol
  • Density 1.5 ± 0.1 g/cm³
  • Boiling Point 345.6 ± 25.0 °C at 760 mmHg
  • Melting Point 113–115 °C
  • Flash Point 177.0 ± 19.7 °C
  • Packaging 25 kg per fiber drum
  • Stocking Term 2–8 °C
  • Product Name
    1. α-Ketoglutaric acid;
    2. 2-Ketoglutaric acid;
    3. 2-oxo-Glutaric acid, alpha-keto
  • Production capacity 3 tons/month
  • Applications Cell culture media material

In cell culture media, α-Ketoglutaric acid helps support cell proliferation by participating in energy metabolism and amino acid biosynthesis. It provides fuel for the TCA cycle and contributes to the production of essential biomolecules, promoting healthier, more active cell growth.

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