Fmoc-L-Thr(tBu)-OH
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Fmoc-L-Thr(tBu)-OH (CAS No. 71989-35-0), also known as N-Fmoc-O-tert-butyl-L-threonine, is a protected amino acid widely used in solid-phase peptide synthesis. It contains a Fmoc group shielding the α-amino function and a tert-butyl group protecting the hydroxyl side chain, allowing selective deprotection during synthesis. This compound plays a key role in assembling GLP-1 analogs such as Semaglutide and Tirzepatide. Offered as a white crystalline powder with 99% min purity, it has a molecular weight of 397.5 g/mol and formula C₁₈H₂₃NO₅. Proper storage at 2–8 °C in a sealed container is recommended to maintain stability.
- CAS No.: 71989-35-0
- Molecular Formula: C₁₈H₂₃NO₅
- Purity: 99% min
- Appearance White crystalline powder
- Molecular Weight 397.5 g/mol
- Density 1.2 ± 0.1 g/cm³
- Boiling Point 581.7 ± 50.0 °C at 760 mmHg
- Melting Point 131–134 °C
- Flash Point 305.6 ± 30.1 °C
- Packaging 25 kg / fibre drum
- Storage Conditions Seal and store at 2–8 °C
- Customs Code 29242990
- Product Name
- Fmoc-Thr(tBu)-OH;
- Fmoc-O-tert-butyl-L-threonine;
- N-(9-Fluorenylmethoxycarbonyl)-O-tert-butyl-L-threonine;
- (2S,3R)-2-(((9-Fluorenylmethoxy)carbonyl)amino)-3-(tert-butoxy)butanoic acid
- Production Capacity 3 ton/month
- Applications Raw material for GLP-1 peptide synthesis, polypeptides, Semaglutide, and Tirzepatide